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Etravirine
4-[6-Amino-5-bromo-2- [(4-cyanophenyl)amino] pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile EMA:Link, US FDA:link 269055-15-4 Intelence, TMC-125, TMC 125, TMC125, Intelence(TM), DAPY deriv, Intelence...
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RO 5114436……..The chemokine receptor CCR5 is a clinically validated target...
RO 5114436 1220514-67-9 CAS OF FREE BASE 1220514-58-8 0F HCL SALT Hoffmann La Roche, 3-Furancarboxamide,...
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Engineered Virus With Dual Protease Key System Opens to Release Gene Therapy
Originally posted on lyranara.me: Viruses cause many diseases but can also serve as vectors for delivery of genetic cargo for therapeutic purposes. Rice University researchers have now modified the...
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Regadenoson……..Adenosine A2a receptor agonist, for Coronary artery disease;...
2-{4-[(methylamino)carbonyl]- 1H-pyrazol-1-yl}adenosine (1-{9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide. US FDA:link 313348-27-5...
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New technique uses ATP as trigger for targeted anti-cancer drug delivery
Originally posted on lyranara.me: Biomedical engineering researchers from North Carolina State University and the University of North Carolina have developed a new technique that uses...
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New method sneaks drugs into cancer cells before triggering release
Originally posted on lyranara.me: A liposome-based co-delivery system composed of a fusogenic liposome encapsulating ATP-responsive elements with chemotherapeutics and a liposome containing ATP was...
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For National Women’s Health Week, FDA Resources Help Women Make Informed...
For National Women’s Health Week, FDA Resources Help Women Make Informed Health Choices By: Marsha B. Henderson, M.C.R.P. “Ask your mother.” In households throughout the country, women often make...
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Amgen-AstraZeneca Psoriasis Drug Brodalumab (AMG 827) Hits Phase 3 Endpoints
AstraZeneca and Amgen announced that the Phase 3 AMAGINE-1TM study evaluating brodalumab in patients with moderate-to-severe plaque psoriasis met all primary and secondary endpoints for both...
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La cantera de los biológicos
Originally posted on biologicos et al.: Los medicamentos biotecnológicos están en plena ebullición, de forma continuada aparecen nuevas moléculas. Muchas de ellas se encuentran en fases preliminares...
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Very First Human Trials Using Cannbis To Treat Brain Cancer Are Under Way
The picture to your left is showing immunofluorescence of the human glioma cell line. (View more pictures here) A European based pharmaceutical company called GW Pharmaceuticals is set...
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BIOSIMILARS MARKET IS NOT EQUIVALENT TO GENERICS MARKET
read this at http://msg-latam-sfb.blogspot.com.ar/2014/05/biosimilars-market-is-not-equivalent-to.htmlFiled under: Biosimilar drugs, COMPANIES, GENERIC DRUG Tagged: BIOSIMILARS MARKET, EQUIVALENT,...
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Pharma Trends: Global Medicine Spending to Pass $1 Trillion in 2014
This year will mark a milestone in the pharmaceutical industry’s growth as drug sales will exceed $1 Trillion. This was the finding of IMS Health in their new report on the spending on pharmaceuticals...
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Ezatiostat……….designed to stimulate the production of blood cells in the bone...
Ezatiostat 168682-53-9 (Ezatiostat); 286942-97-0 (Ezatiostat HCl salt) gamma-Glu-S-BzCys-PhGly diethyl ester HCl; salt, D08917, Ezatiostat hydrochloride Target: glutathione S-transferase P1-1...
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Qingqi Chen’s Book……”Anticancer Drug Research Guide.” New drugs in...
Chen Qingqi, http://chen.medkoo.com/Anticancer-NewDrug.htm Qingqi Chen’s Book “Anticancer Drug Research Guide.” New drugs in development for cancers Filed under: cancer Tagged: CANCER, Qingqi...
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Dovitinib in phase 3 for Cancer, bladder (urothelial carcinoma)
Dovitinib (3E)-4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1,3-dihydrobenzimidazol-2-ylidene]quinolin-2-one, is one kind of white crystalline powder, odorless, little bitter taste....
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Using molecular techniques, researchers improved diagnosis and treatment of...
Originally posted on lyranara.me: The ABC Medical Center, located in Mexico City, implemented various molecular diagnostic methods that can detect the genetic alterations in several types of cancer,...
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Taiho’s Colon Cancer Drug Ups OS in Phase 3
TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride) Taiho’s Colon Cancer Drug Ups OS in Phase 3 Taiho Pharmaceutical Co. Ltd. announced results from its global Phase 3 RECOURSE...
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Timely post on litigation and polymorphism: Case study with Celgene’s Revlimid
Originally posted on Developing the Process: Hi there, folks. It has been a while since I blogged. I decided that I would continue once again and share some of the references that I came across...
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Saracatinib AZD0530 in phase 3 for Ovary Cancer,
Saracatinib NCGC00241099, cas 379231-04-6 893428-71-2 (trihydrate) N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine...
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GSK2606414 is an orally available, potent, and selective PERK inhibitor
GSK2606414 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
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