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Targeting a key driver of cancer

Originally posted on lyranara.me: In a recent breakthrough, a team led by UCSF’s Kevan Shokat was able to exploit a previously unknown “Achilles heel” in K-Ras, part of a family of protein mutations...

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WHITE PAPER: QA/QC: Catching Up With The Competiton

WHITE PAPER: QA/QC: Catching Up With The Competiton By Robert G. McGregor, General Manager, Brookfield Engineering Laboratories, Inc. In the world of pharmaceutical products, there is almost always a...

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DARA BioSciences receives FDA orphan drug designation for KRN5500 (SPK 241)...

KRN5500 Antitumor agent 151276-95-8  cas IUPAC/Chemical name:...

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The five largest Intellectual Property (IP) offices in the world discussed...

Worldwide Intellectual Property Service The five largest Intellectual Property (IP) offices in the world discussed how to further increase co-operation Read more...

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Computer-designed protein triggers self-destruction of Epstein-Barr-infected...

Originally posted on lyranara.me: A small chunk of protein (red) bound to the Epstein-Barr virus target protein (gray) was extended to make a much longer protein, left, and then designed to have a...

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Do salamanders hold the key to limb regeneration?

Originally posted on lyranara.me: This is an image of a salamander (the newt Notophthalmus viridescens). Credit: University College London The secret of how salamanders successfully regrow body parts...

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Developing an improved liposuction technique that melts fat

Originally posted on lyranara.me: Although liposuction is one of the most common and well-established cosmetic surgery procedures in the U.S., it still has its drawbacks. But a new biomedical start-up...

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A better imager for identifying tumors

Originally posted on lyranara.me: This is (a) Optical and mechanical structure of the customized lens with aperture filter and (b) the photograph of the assembled lens, with a quarter for comparison....

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Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?

Originally posted on Pharmaceutical Intelligence: Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View? Author: Larry H. Bernstein, MD, FCAP   A Critical Review What is the...

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Ebola outbreak in West Africa ‘out of control’

Originally posted on Atasteofcreole's Blog: http://www.foxnews.com/health/2014/06/20/ebola-outbreak-in-west-africa-out-control/?intcmp=latestnews A senior official for Doctors Without Borders says the...

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Quantum biology: Algae evolved to switch quantum coherence on and off

Originally posted on lyranara.me: A scanning electron microscope image of cryptophytes. A UNSW Australia-led team has discovered how cryptophytes that survive in very low levels of light are able to...

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An off-switch for drugs’ toxic side effects

Originally posted on lyranara.me: When medications linger in the human body, they sometimes produce toxic side effects.  Professor Alexandros Makriyannis, the George D. Behrakis Trustee Chair in...

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Molecular biology mystery unravelled

Originally posted on lyranara.me: The nature of the machinery responsible for the entry of proteins into cell membranes has been unravelled by scientists, who hope the breakthrough could ultimately be...

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Hetero launches darbepoetin alfa biosimilar in India

The Hetero Group, one of the largest manufacturers and suppliers of activepharmaceutical ingredients to the Indian pharmaceutical industry, yesterdayannounced the launch of its first biosimilar...

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FDA approves Cubist’s Sivextro Tedizolid to treat skin infections

June 21, 2014   Regulators in the USA have given the green light to Cubist Pharmaceuticals’ antibiotic Sivextro for serious skin infections, including those caused by MRSA. The US Food and Drug...

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Sanofi gives back rights to Merrimack cancer drug

After a series of late-stage failures, Sanofi has returned the rights to the cancer compound MM-121 to Merrimack Pharmaceuticals. MM-121, a monoclonal antibody designed to block ErbB3 activation in...

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Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer...

Angiogenesis is a valid target in the treatment of epithelial ovarian cancer. Trebananib inhibits the binding of angiopoietins 1 and 2 to the Tie2 receptor, and thereby inhibits angiogenesis. We aimed...

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Takeda Pharmaceutical

Takeda Pharmaceutical by Dr. Rainer Steinbach Rainer studied chemistry and economics in Germany (Bonn, Marburg) and did postdoctoral work at Stanford University (CA, USA). He held various positions...

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AZD 6564 in preclinical for Antifibrinolytics

AZD 6564 ACS Med. Chem. Lett., 2014, 5 (5), pp 538–543 DOI: 10.1021/ml400526d SYNTHESIS SUPP INFO…..http://pubs.acs.org/doi/suppl/10.1021/ml400526d/suppl_file/ml400526d_si_001.pdf NMR PG 16/32 AS...

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Biocon chief Kiran Mazumdar-Shaw receives Kiel Institute’s ’2014 Global...

The award, established in 2005 by the Kiel Institute, is bestowed upon individuals who have been pioneers in finding solutions to global economic problems. BANGALORE: Biotech major Biocon today said...

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