β-Sitosterol, 후박(厚朴)
β-Sitosterol http://www.herbdb.co.kr/herb/dbsearch3/separation_view.asp?key=302 C29H50O, 414.00 White needles m.p(℃) 283-285 IR(cm-¹) νmax (KBr): 3400, 1680 UV(nm) λmax (MeOH): 216 MS EIMS m/z:...
View ArticleMASITINIB
Masitinib Masitinib; 790299-79-5; Masivet; AB1010; AB-1010; CLASS:Immunomodulator TARGET:KIT (a stem cell factor, also called c-KIT) receptor as well as select other tyrosine kinases STATUS FOR...
View ArticleVX 787 for Avian influenza
(2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridm-3-yl)-5- fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid...
View ArticleIndia’s Strides to buy Aspen’s Australian generic pharmaceutical business
India’s Strides to buy Aspen’s Australian generic pharmaceutical business India-based Strides Arcolab has signed an agreement with subsidiaries of South African drugmaker Aspen Pharmacare Holdings to...
View Article(1S)-(-)-beta-Pinene
(1S)-(1)-beta-Pinene, (1S)-(-)-beta-Pinene . . 13C NMR . . APT . DEPT . COSY . HETCOR IR MASS . . RAMAN (1S)-(1)-beta-Pinene CAS No. 18172-67-3 Chemical Name:...
View ArticleBMS 564929, Androgen receptor (AR) modulator
BMS-564929; BMS564929; 627530-84-1; 2-Chloro-4-[(7r,7as)-7-Hydroxy-1,3-Dioxotetrahydro-1h-Pyrrolo[1,2-C]imidazol-2(3h)-Yl]-3-Methylbenzonitrile; hydantoin, CAS 627530-84-1, Squibb Bristol Myers Co...
View ArticleFDA grants orphan drug status for Lipocine’s LPCN 1107 to prevent preterm birth
17-Hydroxyprogesterone caproate 630-56-8 [(8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate Molecular Weight:...
View ArticleSuzuki cross-coupling in aqueous media
Originally posted on Green Chemistry International: Suzuki cross-coupling in aqueous media Ina Hoffmann,a Bettina Blumenröder,a Silvia Onodi neé Thumann,a Sabine Dommera and Jürgen Schatz*a...
View ArticleAG 014699, Rucaparib
AG014699, AG014699, the phosphate salt of AG14447, which has improved aqueous solubility, has been selected for clinical trial.AG014699 is a tricyclic indole poly(ADP-Ribose) polymerase (PARP)...
View ArticleAN 3485
AN 3485 AN3485, 6-(4-(aminomethyl)-2-chlorophenoxyl)benzo[c][1,2]oxaborol-1(3H)-ol, was synthesized at Anacor Pharmaceuticals as described in patent application WO 2010028005 A1...
View Article7 LAKH VIEWS ON THIS BLOG……NEW DRUG APPROVALS
FLAGS AND HITS 7 LAKH VIEWS HIT ……………..a record and fast reaching 10 lakh views currently in 206 countries THANKS AND REGARD’S DR ANTHONY MELVIN CRASTO Ph.D amcrasto@gmail.com MOBILE-+91 9323115463...
View ArticleBEZ 235 (NVP-BEZ235), Dactolisib
BEZ235 (NVP-BEZ235)Dactolisib 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4, 5-c]quinolin-1-yl]-α,α-dimethyl-benzeneacetonitrile...
View ArticleGefitinib
Gefitinib N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Gefitinib; Iressa; 184475-35-2; ZD1839;...
View ArticleErlotinib
Erlotinib N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy) quinazolin-4-amine Chemical Name: Erlotinib Hydrochloride (Tarceva) Synonyms: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine...
View ArticleWHO publishes final Guideline for Hold-Time Studies
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: After the WHO had released the second draft of the guideline for the design of hold time studies in March already, it now released the final...
View ArticleGatifloxacin
GATIFLOXACIN BMS-206584, CG-5501, AM-1155, Zymar, Bonoq, Gatiflo, AM-1155 (±)-1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Gatifloxacin sold...
View ArticlePravastatin
Pravastatin Sodium CAS : 81131-70-6 (bR,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt sodium...
View ArticleML-236B, Mevastatin (compactin)
Mevastatin (compactin, ML-236B) is a hypolipidemic agent that belongs to the statins class. It was isolated from the mold Penicillium citrinum by Akira Endo in the 1970s, and he identified it as a...
View ArticleAlternative solvents can make preparative liquid chromatography greener
Green Chem., 2015, Advance Article DOI: 10.1039/C5GC00887E, Paper Yao Shen, Bo Chen, Teris A. van Beek...
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