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Acotiamide
Acotiamide hydrochloride trihydrate CAS#: 773092-05-0 (Acotiamide HCl hydrate, 1:1:3); 185104-11-4(Acotiamide HCl, 1:1); 185106-16-5 (Acotiamide free base) Chemical Formula: C21H37ClN4O8S...
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AbbVie: Evaluating Selective JAK1 Inhibitor, for RA Treatment ABT 494
ABT 494 (-)-(3S,4R) cis form CAS 1310726-60-3 FREE FORM MF C17H19F3N6O MW 380.36757 g/mol Tartrate form C17 H19 F3 N6 O . C4 H6 O6 . 4 H2 O ………….CAS 1607431-21-9 1-Pyrrolidinecarboxamide,...
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Ponalrestat
Ponalrestat Phase III An aldose reductase inhibitor potentially for the treatment of diabetes. Imperial Chemical Industries Limited innovator ICI-128436; MK-538; ICI-plc CAS No.72702-95-5 Statil;...
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VAL-083
VAL-083 (1R,2S)-1-((R)-oxiran-2-yl)-2-((S)-oxiran-2-yl)ethane-1,2-diol Galactitol, 1,2:5,6-dianhydro- 1,2:5,6-Dianhydrodulcitol 1,2:5,6-Dianhydrogalactitol 1,2:5,6-Diepoxydulcitol...
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Pacritinib
Pacritinib A Jak2 inhibitor potentially for the treatment of acute myeloid Leukemia and myelofibrosis. ONX-0803; SB-1518 CAS No. 937272-79-2 472.57868 g/mol, C28H32N4O3 S*Bio Pte Ltd. and concert...
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SB 1578
SB1578 ONX 0805 (9E)-15-(2-(Pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26), 15,17,20,22-nonaene...
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Aliskiren
ALISKIREN (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide, CAS 173334-57-1, base CAS...
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AT 9283
AT9283, AT 9283 N-cyclopropyl-N’-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea...
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Breaking and Making of Olefins Simultaneously Using Ozonolysis: Application...
A simple and practical one-pot, two-directional approach to access olefinic esters through simultaneous breaking and making of olefins using ozonolysis of alkenyl aryl selenides is disclosed. The...
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Dr Reddy’s Laboratories Ltd, New patent, WO 2016005960, Liraglutide
!e™A!a™Trp™leu™Va!~-Arg~~GIy-~Arg~~Gly~~OH Formula (I) LIRAGLUTIDE Dr Reddy’s Laboratories Ltd, New patent, WO 2016005960, Liraglutide Process for preparation of liraglutide Kola, Lavanya;...
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Lupin Ltd, New patent, Pitavastatin, WO 2016005919
Formula (1) Lupin Ltd, New patent, Pitavastatin, WO 2016005919 MANE, Narendra, Dattatray; (IN). NEHATE, Sagar, Purushottam; (IN). GODBOLE, Himanshu, Madhav; (IN). SINGH, Girij, Pal; (IN) The present...
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Lupin Ltd, Patent, Pitavastatin, WO2014203045
Lupin Ltd, Patent, Pitavastatin, WO2014203045 A NOVEL, GREEN AND COST EFFECTIVE PROCESS FOR SYNTHESIS OF TERT-BUTYL (3R,5S)-6-OXO-3,5-DIHYDROXY-3,5-O-ISOPROPYLIDENE-HEXANOATE ROY, Bhairabnath; (IN)....
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FDA´s Emerging Technology Applications Program – Draft Guidance
FDA´s Emerging Technology Applications Program – Draft Guidance The FDA recently published a draft guidance for industry on the “Advancement of Emerging Technology Applications”. The draft guidance...
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Regorafenib, SHILPA MEDICARE LIMITED, New patent, WO 2016005874
WO2016005874, PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS SHILPA MEDICARE LIMITED [IN/IN]; 10/80,Second Floor,Rajendra Gunj, Raichur, ರಾಯಚೂರು , karnataka 584102 (IN)...
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BMS 911543
BMS 911543 N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide cas 1271022-90-2 Chemical Formula: C23H28N8O Exact...
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Elotuzumab
Elotuzumab Approved nov 30 2012 A SLAMF7-directed immunostimulatory antibody used to treat multiple myeloma. (Empliciti®) HuLuc-63;BMS-901608 cas 915296-00-3 innovator Elotuzumab (brand name...
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What was the drug in Clinical Trial Tragedy In France Jan 2016
BIA 10-2474 3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide Bial-Portela & Ca. S.A. BIA 10-2474 is an experimental fatty acid amide hydrolase inhibitor[1] developed by the...
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GCC 4401C , GC 2107 , Nokxaban for treating thrombosis
GCC-4401C ( GC-2107), Nokxaban In phase 1 for treating thrombosis 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide...
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Fresolimumab
Fresolimumab GC 1008, GC1008 UNII-375142VBIA cas 948564-73-6 Structure immunoglobulin G4, anti-(human transforming growth factors beta-1, beta-2 (G-TSF or cetermin) and beta-3), human monoclonal...
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