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Commercial Production of Semi-Synthetic Artemisinin
Figure 1. Production of artemisinic acid or β-farnesene by engineered yeast. The sesquiterpene alkenes β-farnesene and amorphadiene are both derived from FPP (farnesyl diphosphate) by the action of...
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Pharmaceutical Manufacturing Encyclopedia, 3rd Edition
View this document on Scribd If you have difficulty in viewing click,,,,,,,,,,http://www.allfordrugs.com/2016/08/07/pharmaceutical-manufacturing-encyclopedia-3rd-edition/ DESCRIPTION This industry...
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Nacubactam, A diazabicyclooctane beta-lactamase inhibitor, for treating...
Nacubactam RG-6080, FPI-1459, OP-0595, WK ?, WK-?, WK? CAS 1452458-86-4, MF C9 H16 N4 O7 S, MW 324.31 Sulfuric acid,...
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DOLUTEGRAVIR, ドルテグラビルナトリウム
Dolutegravir ドルテグラビルナトリウム Soltegravir 2H-Pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)...
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Convert a Drowning Ocean into your Swimming Pool
Convert a drowning ocean into your swimming pool Anthony Melvin Crasto Ph.D Worlddrugtracker, Principal scientist, Process research, Glenmark Pharmaceuticals Ltd If you find a situation in life which...
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Olopatadine
Olopatadine hydrochloride is an antihistamine (as well as anticholinergic and mast cell stabilizer), sold as a prescription eye dropmanufactured by Alcon in one of three strengths: 0.7% solution or...
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DAROLUTAMIDE
Darolutamide N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide N-((S)- 1 -(3-(3-chloro-4-cyanophenyl)- lH-pyrazol- 1...
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Flow Grignard and Lithiation: Screening Tools and Development of Continuous...
ORGANIC CHEMISTRY SELECT Efficient continuous Grignard and lithiation processes were developed to produce one of the key regulatory starting materials for the production of edivoxetine hydrochoride....
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High Throughput Enzymatic Enantiomeric Excess: Quick-ee
Green Chemistry International . High throughput screening techniques (HTS) are fast and efficient alternatives to evaluate enzymatic activities. Here, this technique is applied to obtain enantiomeric...
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The continuous flow Barbier reaction: an improved environmental alternative...
Green Chemistry International A key pharmaceutical intermediate (1) for production of edivoxetine·HCl was prepared in >99% ee via a continuous Barbier reaction, which improves the greenness of the...
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ULIXERTINIB, уликсертиниб , أوليكسيرتينيب , 优立替尼 ,
OR ULIXERTINIB 4-(5-chloro-2-isopropylaminopyridin-4-yl)-1H-pyrrole-2-carboxylic acid[1-(3-chlorophenyl)-2-hydroxyethyl]amide Molecular Formula: C21H22Cl2N4O2 Molecular Weight: 433.33098 g/mol...
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CDMO Ash Stevens to Be Acquired by Piramal Enterprises
Piramal Enterprises Limited announced that its wholly owned subsidiary in the U.S. has entered into an agreement to acquire 100 percent stake in Ash Stevens Inc., a U.S.-based contract development and...
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AZD-1236 Revisited
AZD1236 CAS 459814-89-2, MF C15 H19 Cl N4 O5 S. MW402.85 2,4-Imidazolidinedione, 5-[[[4-[(5-chloro-2-pyridinyl)oxy]-1-piperidinyl]sulfonyl]methyl]-5-methyl-, (5S)-...
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Osanetant , SR-142,801
Osanetant (SR-142,801) 160492-56-8 CAS : MW 605.257582985 Chemical Formula C35H41Cl2N3O2...
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WHAT ARE SUPERGENERICS
DRUG REGULATORY AFFAIRS INTERNATIONAL View original postFiled under: Uncategorized
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NEW BLOG: DRUG APPROVALS INTERNATIONAL
LINK http://drugapprovalsint.com/ http://drugapprovalsint.com/ http://drugapprovalsint.com/ http://drugapprovalsint.com/ /////////////Filed under: Anthony crasto, BLOGS Tagged: Anthony crasto,...
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Two new FDA Warning Letters for API Manufacturers in China
DRUG REGULATORY AFFAIRS INTERNATIONAL Two new FDA Warning Letters for API Manufacturers in China In June 2016, two API manufacturers in China received a Warning Letter from the FDA. Both companies had...
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Is AQL Testing required within the 100% Visual Inspection?
DRUG REGULATORY AFFAIRS INTERNATIONAL Is AQL Testing required within the 100% Visual Inspection? One of the most frequently asked questions is whether an additional testing based on samples is...
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ACT-334441, Cenerimod an S1P receptor 1 agonist
ACT-334441 Cenerimod UNII-Y333RS1786; Y333RS1786 S1P receptor 1 agonist CAS 1262414-04-9 Chemical Formula: C25H31N3O5 Exact Mass: 453.22637 Actelion Pharmaceuticals Ltd. Martin Bolli, Cyrille Lescop,...
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RPL 554
RPL-554 Molecular FormulaC26H31N5O4 Average mass477.555 RPL 554 Urea, N-[2-[(2E)-6,7-dihydro-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl]ethyl]-...
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