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Tadalafil (cialis)

Tadalafil GF-196960, IC-351, Cialis 6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido[3,4-b]indole-1,4-dione...

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Grape Seeds Fight Bowel Cancer

Originally posted on lyranara.me: University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as...

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FDA Approves Vimizim to Treat Mucopolysaccharidosis Type IVA

STRUCTURAL FORMULA Monomer APQPPNILLL LMDDMGWGDL GVYGEPSRET PNLDRMAAEG LLFPNFYSAN 50 PLCSPSRAAL LTGRLPIRNG FYTTNAHARN AYTPQEIVGG IPDSEQLLPE 100 LLKKAGYVSK IVGKWHLGHR PQFHPLKHGF DEWFGSPNCH FGPYDNKARP...

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IkB kinase inhibitors , SANOFI, for osteoarthritis

K salt monohydrate, N-​[[2-​[2-​(methylamino)​-​4-​pyrimidinyl]​-​1H-​indol-​5-​yl]​carbonyl]​-​3-​(phenyl-​2-​pyridinylamino)​-   L-​Alanine, 2-{[2-(2-methylamino-pyrimidin-4-yl)-lH-indole-5-...

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Researchers discover how cancer ‘invisibility cloak’ works

Originally posted on lyranara.me: Researchers at National Jewish Health have discovered how a lipid secreted by cancer tumors prevents the immune system from mounting an immune response against it....

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The US FDA has issued full approval for Israeli drugmaker Teva’s Synribo...

Omacetaxine mepesuccinate 高三尖杉酯碱 Alkaloid from Cephalotaxus harringtonia; FDA approved orphan drug status for Ceflatonin in the treatment of chronic myeloid leukemia due to being an inducer of...

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The secret of fertile sperm

Originally posted on lyranara.me: Progesterone and other fatty signaling molecules are critical for sperm fertility. Credit: C. Cain To better understand the causes of male infertility, a team of Bay...

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MOXIFLOXACIN, Bay-12-8039

MOXIFLOXACIN Bay-12-8039 US FDA:link CAS 354812-41-2 186826-86-8 HYDROCHLORIDE  1-cyclopropyl-7-[(1S,6S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo- quinoline-3-carboxylic acid...

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FDA Breakthrough Therapy Designation: Fourth Drug Receives FDA Approval

Originally posted on Orphan Druganaut Blog: . The FDA approves on February 12, the fourth drug to have the coveted Breakthrough Therapy Designation (BTD). The approval is for orphan drug Imbruvica...

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Sonidegib/Erismodegib..Novartis Cancer Drug LDE225 Meets Primary Endpoint in...

Sonidegib/Erismodegib CODE DESIGNATION ..LDE225, NVP-LDE-225 Treatment of medulloblastoma PHASE3 2014 FDA FILING Treatment of advanced basal cell carcinoma PHASE3 2014 FDA FILING Treatment of SOLID...

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Cinnamon cuts blood glucose levels in diabetes patients

Originally posted on lyranara.me: Consumption of cinnamon is associated with favorable reductions in plasma glucose and lipid levels, according to research published in the September/October issue of...

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FDA Accepts Filing of NDA for IV Antibiotic Oritavancin with Priority Review

Oritavancin (4R)-22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabinohexopyranosyl)-N3-(p-(p-chlorophenyl)benzyl)vancomycin (3S, 6R, 7R, 22R, 23S, 26S, 36R, 38aR) -22 – (3-Amino-2...

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KW-4490 A PDE4 inhibitor from Kyowa Hakko Kirin

KW 4490 cis-4-Cyano-4-(2,3-dihydro-8-methoxy-1,4-benzodioxin-5-yl)cyclohexanecarboxylic Acid  Cyclohexanecarboxyli​c acid, 4-​cyano-​4-​(2,​3-​dihydro-​8-​methoxy-​1,​4-​benzodioxin-​5-​yl)​-​, cis-...

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Immune cells regulate blood stem cells

Originally posted on lyranara.me: Blood stem cell cultures: Blood stem cells from colonies (cell clusters) in vitro consisting of different blood cells. Nine blood stem cell colonies are illustrated...

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Vertex Pharmaceuticals: Another Step Forward For Kalydeco

Originally posted on Orphan Druganaut Blog: . On February 21st, Vertex Pharmaceuticals announces that the FDA approves a supplemental New Drug Application (sNDA) for orphan drug Kalydeco (Ivacaftor)...

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RAMELTEON, TAK 375 ..Melatonin MT1/MT2 receptor agonist

RAMELTEON ACN-S001714, ZINC00007031  HSDB 7787 Ramelteon Rozerem TAK-375 UNII-901AS54I69 Molecular Formula: C16H21NO2   Molecular Weight: 259.34344 CAS number 196597-26-9...

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Regulatory Considerations for Biosimilars

Biological medicines are already becoming an increasingly important part of health care. With patent expiries on originator biological products, biosimilars are also increasingly become a part of this...

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FDA Approves BMS Drug for Rare Fat Disorder

CHEMICAL NAMES 1. Leptin (human), N-methionyl- 2. N-methionylleptin (human) STRUCTURAL FORMULA MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL 50 TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV...

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Bhasma : The ancient Indian nanomedicine

Bhasma : The ancient Indian nanomedicine Dilipkumar pal Department of Pharmaceutical Sciences, Guru Ghasidash Vishwavidyalya (A Central University), Koni, Bilaspur – 495 009, Chhattisgarh  India...

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What Does 100% of Your Daily Value of Cholesterol Look Like?

Healthline just published an interesting infograph that gives a visualization of what your daily value of cholesterol looks like.  In the graphic, you can see what 300 mg of cholesterol looks like for...

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