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Topiroxostat for gout and hyperuricemia
Topiroxostat Xanthine oxidase inhibitor FOR GOUT AND HYPERURICEMIA Launched – 2013, Fuji YakuhinSanwa, Topiloric Uriadec IUPAC Name: 4-(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile...
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SUMATRIPTAN …Avanir files new drug application for migraine drug
SUMATRIPTAN, GR-43175 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]- N-methyl-methanesulfonamide 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide Formula C14H21N3O2S Mol. mass 295.402...
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FDA Breakthrough Therapy Designation: 32 And Counting
Reblogged from Orphan Druganaut Blog: On February 3rd, GlaxoSmithKline (GSK) announces that Promacta (US)/Revolade (Europe) (Eltrombopag) receives the coveted FDA Breakthrough Therapy Designation...
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How to Handle Drug Polymorphs… Case Study of Trelagliptin Succinate
Pharmaceutical API Polymorphs… case study of Trelagliptin CASE STUDY WITH..Compound I having the formula WO2008067465A1 OR US8084605 IS THE PATENT USED AND WITH FORM “A” AND AMORPHOUS FORM Active...
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Lysosomal Storage Disorders: Advocacy Group Receives FDA Orphan Designations
Reblogged from Orphan Druganaut Blog: This is the second Blog Post in a series over the next week that will examine Lysosomal Storage Disorders (LSDs) in the rare disease and orphan drug space. This...
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Biogen’s multiple sclerosis drug Tecfidera obtains EU approval
US-based Biogen Idec has received approval from the European Commission (EC) for its Tecfidera (dimethyl fumarate) as a first-line oral treatment for people with relapsing-remitting multiple sclerosis...
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FDA grants breakthrough therapy designation to Promacta (EU trade name:...
Earlier this week, Ligand Pharmaceuticals Inc. ( LGND ) announced that the U.S. Food and Drug Administration (FDA) granted breakthrough therapy designation to Promacta (EU trade name: Revolade)....
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Eluxadoline …Diarrhea-predominant irritable bowel syndrome
Eluxadoline 5 JAN 2014 Furiex Pharmaceuticals Inc. more than doubled in its best day of trading after its experimental drug alleviated diarrhea and abdominal pain caused by irritable bowel syndrome...
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FONDAPARINUX
FONDAPARINUX Fondaparinux is a drug belonging to the group of the antithrombotic agents and are used to prevent deep vein thrombosis in patients undergoing orthopedic surgery. It is also used for the...
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Why FDA Supports a Flexible Approach to Drug Development
By: Margaret A. Hamburg, M.D. We all know that just as every person is different, so too is every disease and every drug. And so we weren’t surprised by the results of a new study published in the...
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HEPARIN SODIUM
HEPARIN SODIUM LAUNCHED 1937 9041-08-1 NA SALT 9005-49-6 (heparin) Thromboliquine, Calciparine, Certoparin, Dalteparin, Fraxiparin, Heparinate, Multiparin, Novoheparin, Parnaparin Unfractionated...
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Idrabiotaparinux for anticoagulant therapy.
Idrabiotaparinux 抗血栓治療中の出血率を低下させるためのイドラビオタパリナックスの使用 (biotinylated idraparinux, SSR-126517, SSR-126517E) Idrabiotaparinux has an attached biotin moiety at the non-reducing end unit, which allows its...
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Triphala : A Digestive Miracle
Emblica officinalis Triphala (/triːˈfɑːlə/ or /triːˈfælə/; Hindi/Sanskrit: त्रिफला, triphalā [trɪˈpʰɐlaː], “three fruits”)[1] is an Ayurvedic[2] herbal rasayana formula consisting of equal parts of...
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ERTUGLIFLOZIN
ERTUGLIFLOZIN, PFIZER THERAPEUTIC CLAIM Treatment of type 2 diabetes CHEMICAL NAMES 1. β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- 2....
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Garden Cress Extract Kills 97% of Breast Cancer Cells in Vitro
Garden Cress Extract Kills 97% of Breast Cancer Cells in Vitro: Garden cress, like broccoli, is a cruciferous-family vegetable but is unique because it contains very high amounts of BITC (benzyl...
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ASPARAGUS AND THE SMELL
ASPARAGUS Asparagusic acid Asparagusic acid is the organosulfur with the formula S2(CH2)2CHCO2H. The molecule contains both carboxylic acid and disulfide functional groups. It is present in the...
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Scientists develop potential new drug treatment to tackle viruses
Originally posted on lyranara.me: An international team of scientists have successfully developed a novel compound which early signs suggest might prevent a range of viruses from infecting humans....
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Fiduxosin ….An α1-Adrenoceptor antagonist
Fiduxosin Fiduxosin hydrochloride, 208992-74-9, NCGC00162178-02, AC1L58WW, A-185980.1,ABT-980,UNII-W9O92HYT6I Molecular Formula: C30H30ClN5O4S Molecular Weight: 592.1083...
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Flow chemistry approaches directed at improving chemical synthesis
Flow synthesis offers many advantages when applied to the processing of difficult or dangerous chemical transformations. Furthermore, continuous production allows for rapid scale up of reactions...
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