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New pain relief targets discovered
Originally posted on lyranara.me: The immune cell enters the nerve. Credit: Dr. Marzia Malcangio, King’s College London Scientists have identified new pain relief targets that could be used to provide...
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Enzyme revealed as promising target to treat asthma and cancer
Originally posted on lyranara.me: In experiments with mice, Johns Hopkins Kimmel Cancer Center scientists have identified an enzyme involved in the regulation of immune system T cells that could be a...
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OMARIGLIPTIN. MK 3102 IN PHASE 3 FOR TYPE 2 DIABETES
OMARIGLIPTIN. MK 3102 1226781-44-7 (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine...
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Teva Pharmaceutical has been given a green light by the European Commission...
lipegfilgrastim C 864 H 1369 N 225 O 258 S 9 [C 2 H 4 O] N 117844-87-7 pegylated granulocyte colony stimulating factor; O3.133-[N5-(N-{[ω-methoxypoly (oxyethylene)] carbonyl} glycyl)-α-neuraminyl-(2 →...
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Boehringer’s first cancer drug leads EMA recommendations Afatinib recommended...
Afatinib 439081-18-2 850140-73-7 dimaleate Tovok, BIBW2992, Tomtovok Boehringer Ingelheim Int, An irreversible EGFR/HER2 inhibitor Molecular Weight: 485.94 Molecular Formula: C24H25ClFN5O3...
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Study identifies promising target for new drugs to treat lethal form of brain...
Originally posted on Syn-Org-Chemist: Study identifies promising target for new drugs to treat lethal form of brain cancer . View originalFiled under: Uncategorized
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(Z)-5-((1-(4-Chloro-2-(trifluoromethyl)benzyl)-1H-indazol-5-yl)methylene)-3-(...
Janssen Pharmaceutica Nv innovator for the treatment of hyperglycemia in patients with type 2 diabetes mellitus. 2,4-Thiazolidinedione,...
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Evacetrapib, LY2484595 for Treatment of high cholesterol and preventing...
Evacetrapib, LY2484595 Evacetrapib is an experimental drug being investigated to raise high-density lipoprotein cholesterol (HDL-C) via inhibition of the cholesteryl ester transfer protein (CETP)...
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Novel Oxazolidinone Antibacterial Candidate FYL-67...
cas no 1416314-55-0 C20 H18 F N5 O3 FYL-67 IS HYDROCHLORIDE (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxo-oxazolidin-5-yl)methyl)acetamide...
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FDA Approves Cyramza, ramucirumab (IMC-1121B) for Stomach Cancer
April 21, 2014 — The U.S. Food and Drug Administration today approved Cyramza (ramucirumab) to treat patients with advanced stomach cancer or gastroesophageal junction adenocarcinoma, a form of...
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Novel Diacylglycerol Acyltransferase-1 (DGAT-1)...
1236408-39-1 C19 H19 N5 O2 US 20100197591 Inventores Gary E. Aspnes, Robert L. Dow, Michael J. Munchhof Beneficiário Original Pfizer Inc...
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Antimalarials………….Arterolane from Ranbaxy
664338-39-0 Arterolane 664338-39-0, UNII-3N1TN351VB, OZ277, RBX-11160, NCGC00274173-01 Molecular Formula: C22H36N2O4 Medicines For Malaria Venture Mmv Ranbaxy Lab Ltd Molecular Weight: 392.53224...
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ACT-280778 is a L/T calcium channel blocker potentially indicated for the...
ACT-280778 (1R,2R,4R)-2-(2-((3-(4,7-Dimethoxy-1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-5-phenylbicyclo[2.2.2]oct-5-en-2-yl Isobutyrate Propanoic acid, 2-methyl-,...
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How the body fights against viruses
Originally posted on lyranara.me: Illustration “structure”: This is a model of the RNA-binding domain of ADAR1 (green), bound to double-stranded RNA (yellow). Transportin1, which mediates the nuclear...
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Erectile dysfunction can be reversed without medication
Originally posted on lyranara.me: Men suffering from sexual dysfunction can be successful at reversing their problem, by focusing on lifestyle factors and not just relying on medication, according to...
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RG 7388 is a MDM2 inhibitor with superior potency and selectivity in phase 1...
RG-7388 Hoffmann-La Roche, Inc. , INNOVATOR 4-((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid...
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New method to analyse how cancer cells die
Originally posted on lyranara.me: A team from The University of Manchester – part of the Manchester Cancer Research Centre – have found a new method to more efficiently manufacture a chemical used to...
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New treatment could ‘protect against any strain of the flu’
Originally posted on lyranara.me: The new biologic (green) binding to the surface of cells (blue nuclei), protecting the cells from invasion by the influenza virus. Scots scientists have developed a...
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An easier, safer, and more accurate treatment for pancreatic cancer
Originally posted on lyranara.me: (a) A single axial slice of the pancreas from the pre-treatment CT scans is overlaid with computed contours of light fluence levels around the fiber location. This...
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ALK Inhibitor CEP-28122
(1S,2S,3R,4R)-3-[5-Chloro-2-(S)-1-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]bicycle[2.2.1]hept-5-ene-2-carboxylic Acid Amide...
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