Fibroblasts could offer alternative to heart transplants
Originally posted on lyranara.me: Cardiac fibroblasts Fibroblasts, cells long thought to be boring and irrelevant, could offer an alternative to heart transplants for patients with heart disease....
View ArticleANTHONYFLOZIN………Find one if you can in this review
find here http://medcheminternational.blogspot.in/p/flozin-series.html 1 TOFOGLIFLOZIN 2 SERGLIFLOZIN 3 DAPAGLIFLOZIN 4 IPRAGLIFLOZIN 5 EMPAGLIFLOZIN 6 LUSEOGLIFLOZIN 7 REMOGLIFLOZIN 8 ERTUGLIFLOZIN...
View ArticleRadiation therapy to treat uterine cancer linked with increased risk of...
Originally posted on lyranara.me: Radiation therapy used to treat uterine cancer may increase a patient’s risk of developing bladder cancer. That is the conclusion of a recent study published in BJU...
View Article(S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(1H-tetrazol-1-yl)phenyl)acryloyl)-5-(4-me...
(S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(lH-tetrazol-l-yl)phenyl)acryloyl)-5 -(4-methyl-2-oxopiperazin- 1 -yl)- 1,2,3 ,4-tetrahydroisoquinoline- 1 -carboxamido)benzoic acid...
View ArticleSprifermin offers benefit for cartilage loss from knee osteoarthritis
Originally posted on lyranara.me: In a new study in patients with osteoarthritis (OA) of the knee, at 12 months, total femorotibial cartilage thickness loss was reduced in sprifermin (recombinant...
View ArticleSphaelactone dimethylamine fumarate
Sphaelactone dimethylamine fumarate Accenda Tech Co Ltd; Nankai University Acute leukemia Protein farnesyltransferase inhibitor; Ras GTPase inhibitor Accendatech, 天津尚德药缘科技有限公司,Nankai University,...
View ArticleGSK3β inhibitor, AZD8926
[4-[5-Fluoro-4-[3-tetrahydropyran-4-yl-2-(trifluoromethyl)imidazol-4-yl]-pyrimidin-2-yl]aminophenyl]-(4-methylpiperazin-1-yl)-methanone [4- [5-Fluoro-4- [3-tetr ahydropy r an-4-yl-2-(trifluor...
View ArticleWater molecules control inactivation and recovery of potassium channels
Originally posted on lyranara.me: Depiction of simulated potassium channel and surrounding environment. Potassium ions (green) are unable to pass through because water molecules (red and white) are...
View ArticleFDA Approves Zykadia, Ceritinib, LDK378 for ALK-Positive NSCLC
Ceritinib (LDK378) mw 558.14, C28H36ClN5O3S, CAS 1032900-25-6 NVP-LDK378, NVP-LDK378-NX Novartis Ag innovator 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)...
View ArticleTafenoquine…..GSK Launches Phase 3 Malaria Drug Trials
Tafenoquine N-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine WR-238605, WR 238605, cas no 106635-80-7,...
View ArticleGlenmark Kicks Off Monoclonal Antibody Pain Studies
Glenmark Pharmaceuticals S.A., a wholly owned Swiss subsidiary of Glenmark Pharmaceuticals Ltd., announced that GBR 900, a novel monoclonal antibody is entering human trials. GBR 900 targets TrkA,...
View ArticleNew Developments in Container Closures and Delivery Devices for...
Originally posted on AAPS Blog: by Satish Singh All product development scientists understand the importance of container closure to the sterility, stability, and delivery of a parenteral drug,...
View ArticleMerimepodib; VX-497 selective IMPDH inhibitor and immunosuppressive agent
Merimepodib; VX-497; VX497; VX 497; MMP, VI21497; VI-21497; VI 21497. 198821-22-6 (S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate...
View ArticleWhey beneficially affects diabetes and cardiovascular disease risk factors in...
Originally posted on lyranara.me: Whey protein has been demonstrated to improve fasting lipid and insulin response in overweight and obese individuals. To establish new hypotheses for this effect and...
View ArticleBulaquine a CDRI India Antimalarial
Bulaquine CAS NO.: 79781-00-3 2(3H)-Furanone, dihydro-3-(1-((4-((6-methoxy-8-quinolinyl)amino)pentyl)amino)ethylidene)-, 3-[l-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]-...
View ArticleSanfilippo Syndrome: FDA Orphan Designations For Gene Therapy
Originally posted on Orphan Druganaut Blog: Abeona Therapeutics , a Cleveland-based biotechnology start-up, is created in March 2013 as a spinoff of Nationwide Children’s Hospital , with the goal of...
View ArticleStem cell therapy regenerates heart muscle damaged from heart attacks in...
Originally posted on lyranara.me: Heart cells created from human embryonic stem cells successfully restored damaged heart muscles in monkeys. The results of the experiment appear in the April 30...
View ArticleResveratrol remains effective against cancer after the body converts it
Originally posted on lyranara.me: A chemical found in red wine remains effective at fighting cancer even after the body’s metabolism has converted it into other compounds. This is an important finding...
View ArticleRevision of the USP Chapter on Spectroscopic Methods
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Revision of the USP Chapter on Spectroscopic Methods A new concept for the representation of different analytical and spectroscopic methods...
View ArticlePharmaceutical Packaging – New USP Proposal for Optimised Method of Measuring...
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Pharmaceutical Packaging – New USP Proposal for Optimised Method of Measuring Moisture Vapour Permeation An improved method of measuring...
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