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Fibroblasts could offer alternative to heart transplants

Originally posted on lyranara.me: Cardiac fibroblasts Fibroblasts, cells long thought to be boring and irrelevant, could offer an alternative to heart transplants for patients with heart disease....

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ANTHONYFLOZIN………Find one if you can in this review

find here http://medcheminternational.blogspot.in/p/flozin-series.html   1 TOFOGLIFLOZIN 2 SERGLIFLOZIN 3 DAPAGLIFLOZIN 4 IPRAGLIFLOZIN 5 EMPAGLIFLOZIN 6 LUSEOGLIFLOZIN 7 REMOGLIFLOZIN 8 ERTUGLIFLOZIN...

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Radiation therapy to treat uterine cancer linked with increased risk of...

Originally posted on lyranara.me: Radiation therapy used to treat uterine cancer may increase a patient’s risk of developing bladder cancer. That is the conclusion of a recent study published in BJU...

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(S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(1H-tetrazol-1-yl)phenyl)acryloyl)-5-(4-me...

(S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(lH-tetrazol-l-yl)phenyl)acryloyl)-5 -(4-methyl-2-oxopiperazin- 1 -yl)- 1,2,3 ,4-tetrahydroisoquinoline- 1 -carboxamido)benzoic acid...

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Sprifermin offers benefit for cartilage loss from knee osteoarthritis

Originally posted on lyranara.me: In a new study in patients with osteoarthritis (OA) of the knee, at 12 months, total femorotibial cartilage thickness loss was reduced in sprifermin (recombinant...

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Sphaelactone dimethylamine fumarate

  Sphaelactone dimethylamine fumarate Accenda Tech Co Ltd; Nankai University Acute leukemia Protein farnesyltransferase inhibitor; Ras GTPase inhibitor Accendatech, 天津尚德药缘科技有限公司,Nankai University,...

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GSK3β inhibitor, AZD8926

[4-[5-Fluoro-4-[3-tetrahydropyran-4-yl-2-(trifluoromethyl)imidazol-4-yl]-pyrimidin-2-yl]aminophenyl]-(4-methylpiperazin-1-yl)-methanone  [4- [5-Fluoro-4- [3-tetr ahydropy r an-4-yl-2-(trifluor...

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Water molecules control inactivation and recovery of potassium channels

Originally posted on lyranara.me: Depiction of simulated potassium channel and surrounding environment. Potassium ions (green) are unable to pass through because water molecules (red and white) are...

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FDA Approves Zykadia, Ceritinib, LDK378 for ALK-Positive NSCLC

Ceritinib (LDK378) mw 558.14, C28H36ClN5O3S, CAS 1032900-25-6   NVP-LDK378, NVP-LDK378-NX  Novartis Ag  innovator 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)...

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Tafenoquine…..GSK Launches Phase 3 Malaria Drug Trials

  Tafenoquine N-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine WR-238605, WR 238605, cas no 106635-80-7,...

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Glenmark Kicks Off Monoclonal Antibody Pain Studies

    Glenmark Pharmaceuticals S.A., a wholly owned Swiss subsidiary of Glenmark Pharmaceuticals Ltd., announced that GBR 900, a novel monoclonal antibody is entering human trials. GBR 900 targets TrkA,...

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New Developments in Container Closures and Delivery Devices for...

Originally posted on AAPS Blog: by Satish Singh All product development scientists understand the importance of container closure to the sterility, stability, and delivery of a parenteral drug,...

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Merimepodib; VX-497 selective IMPDH inhibitor and immunosuppressive agent

    Merimepodib; VX-497; VX497; VX 497; MMP, VI21497; VI-21497; VI 21497. 198821-22-6 (S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate...

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Whey beneficially affects diabetes and cardiovascular disease risk factors in...

Originally posted on lyranara.me: Whey protein has been demonstrated to improve fasting lipid and insulin response in overweight and obese individuals. To establish new hypotheses for this effect and...

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Bulaquine a CDRI India Antimalarial

  Bulaquine CAS NO.: 79781-00-3 2(3H)-Furanone, dihydro-3-(1-((4-((6-methoxy-8-quinolinyl)amino)pentyl)amino)ethylidene)-,  3-[l-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]-...

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Sanfilippo Syndrome: FDA Orphan Designations For Gene Therapy

Originally posted on Orphan Druganaut Blog: Abeona Therapeutics , a Cleveland-based biotechnology start-up, is created in March 2013 as a spinoff of Nationwide Children’s Hospital , with the goal of...

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Stem cell therapy regenerates heart muscle damaged from heart attacks in...

Originally posted on lyranara.me: Heart cells created from human embryonic stem cells successfully restored damaged heart muscles in monkeys. The results of the experiment appear in the April 30...

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Resveratrol remains effective against cancer after the body converts it

Originally posted on lyranara.me: A chemical found in red wine remains effective at fighting cancer even after the body’s metabolism has converted it into other compounds. This is an important finding...

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Revision of the USP Chapter on Spectroscopic Methods

Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Revision of the USP Chapter on Spectroscopic Methods A new concept for the representation of different analytical and spectroscopic methods...

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Pharmaceutical Packaging – New USP Proposal for Optimised Method of Measuring...

Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Pharmaceutical Packaging – New USP Proposal for Optimised Method of Measuring Moisture Vapour Permeation An improved method of measuring...

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