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FDA approves new type of sleep drug, Belsomra
The FDA has approved a new type of sleep drug. This new drug is an orexin receptor antagonist and is the first approved drug of this type. Orexins are chemicals that are involved in regulating the...
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ABACAVIR…….For the treatment of HIV-1 infection, in combination with other...
Chemical structure of abacavir {(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol...
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Ebola – What’s the Pipeline?
Originally posted on IHS Healthcare and Pharma Blog: As the 2014 West Africa Ebola virus outbreak claims its thousandth victim, many questions are being asked over how the disease can be contained,...
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Carbohydrate Metabolism
Originally posted on Pharmaceutical Intelligence: Carbohydrate Metabolism Larry H. Bernstein, MD, FCAP, Reporter and Curator Leaders in Pharmaceutical Intelligence...
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Valdecoxib
Valdecoxib CAS Registry Number: 181695-72-7 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide Manufacturers’ Codes: SC-65872 Bextra (Pharmacia & Upjohn) Molecular Formula: C16H14N2O3S...
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FDA approves Avastin to treat patients with aggressive and late-stage...
August 14, 2014 The U.S. Food and Drug Administration today approved a new use for Avastin (bevacizumab) to treat patients with persistent, recurrent or late-stage (metastatic) cervical cancer....
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HALOPERIDOL
Haloperidol /hæloʊpɛridɒl/ (INN, BAN, USAN, AAN; most common brand names: Haldol, Serenace) is an antipsychotic medication used in the treatment of schizophrenia, acute psychosis, mania,...
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Drug discovery: Past and present
The field of biotechnology has revolutionized the drug discovery process. Recombinant DNA-driven drug discovery process is beginning to add new avenues for some old drugs. In its infancy, genetic...
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Drug discovery: a view through the looking glass
Liposome microarray technology is a new solution to the growing costs of drug discovery [1]. As numerous blockbuster drugs’ patents expire and regulatory requirements for new drugs tighten, the...
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Macrocycles in new drug discovery
Macrocycles in new drug discovery Jamie Mallinson, Ian Collins Future Medicinal Chemistry, Jul 2012, Vol. 4, No. 11, Pages 1409-1438. Summary | Full Text | PDF (3354 KB) | PDF Plus (3440 KB) | Add to...
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Higher-Order Structure Comparability: Case Studies of Biosimilar Monoclonal...
Figure 1a: Diagram of the antibody array enzyme-linked immunosorbent assay (ELISA) Figure 1b: ELISA format for the antibody array technology Great successes for monoclonal antibody (MAb)–based...
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THE GROWING IMPACT OF CLICK CHEMISTRY ON DRUG DISCOVERY
The growing impact of click chemistry on drug discovery HC Kolb, KB Sharpless – Drug discovery today, 2003 – Elsevier Click chemistry is a modular approach that uses only the most practical and...
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Lipid Metabolism
Originally posted on Pharmaceutical Intelligence: Lipid metabolism Larry H. Bernstein, MD, FCAP, Reporter and Curator Leaders in Pharmaceutical Intelligence...
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Neuroprotective effects of Asiaticoside – a Saponin of Centella asiatica
Originally posted on Clinicalnews.org: PUBLIC RELEASE DATE: 10-Aug-2014 In the central nervous system, Asiaticoside has been shown to attenuate in vitro neuronal damage caused by exposure to...
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WHO issues draft proposal for biosimilar naming
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: A long debate is ongoing about biosimilar naming around the world. Although EU accepted the same INN system years ago, with the latest...
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Directing Venom To Fight Cancer ACS Meeting News: Encapsulated venom peptide...
Originally posted on ORGANIC CHEMISTRY SELECT: Scorpion toxins may one day be useful as anticancer drugs. Credit: Courtesy of Dipanjan Pan Venom from scorpions or honeybees sounds like it wouldn’t...
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REFLECTION PAPER ON NANOTECHNOLOGY-BASED MEDICINAL PRODUCTS FOR HUMAN USE
Nanotechnology Nanotechnology is the use of tiny structures – less than 1,000 nanometres across – that are designed to have specific properties. Nanotechnology is an emerging field in science that is...
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Кальцитонин, Calcitonin
Molecular formula of calcitonin is C145H241N43O49S2• Molecular weight is 3434.8 g/mol Calcitonin-related polypeptide alpha NMR solution structure of salmon calcitonin in SDS micelles.[1] Calcitonin...
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Zopolrestat
Zopolrestat CAS : 110703-94-1 110765-49-6 (Na salt) 3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid 2- [4-Oxo-3- [5- (trifluoromethyl)...
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Celltrion files Remsima in the United States
Celltrion files Remsima in the United States: Celltrion announced that the company, on August 8, 2014, completed the filing procedure to obtain US FDA approval for its infliximab biosimilar. This...
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