Clik here to view.
Elemental Impurity Analysis in Pharmaceuticals.free download from Butterworth...
Elemental Impurity Analysis in Pharmaceuticals A method to identify the presence of heavy metals in pharmaceuticals was introduced in the United States Pharmacopeia more than 100 years ago....
View ArticleClik here to view.
Automation of Process Control within the Pharmaceutical Industry
Automation of Process Control within the Pharmaceutical Industry While most pharmaceutical businesses have adopted process automation in one format or another, the technology has evolved considerably...
View ArticleClik here to view.
Radius Announces Positive Phase 3 Top-Line Results for Its Investigational...
Abaloparatide WALTHAM, Mass., Dec. 21, 2014 (GLOBE NEWSWIRE) — Radius Health, Inc. today announced positive top-line 18-month fracture results from the Company’s Phase 3 clinical trial (ACTIVE)...
View ArticleClik here to view.
Brivanib alaninate ブリバニブアラニンエステル
BMS-582664, brivanib alaninate ((S)-((R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl) 2-aminopropanoate Brivanib alaninate is a new oncology...
View ArticleClik here to view.
Bafetinib
Bafetinib 4-[[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl]-N-[4-methyl-3-[(4-pyrimidin-5-ylpyrimidin-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide, cas 859212-16-1...
View ArticleClik here to view.
Foretinib (Exelixis, GlaxoSmithKline, XL-880)
Foretinib (Exelixis, GlaxoSmithKline) (XL-880) CAS No.：849217-64-7, 937176-80-2 Formula：C34H34F2N4O6 M.Wt：632.24 GSK1363089, XL880...
View ArticleClik here to view.
MSA 100 a serotonin receptor antagonist.
(2E)-N-[2-[2-[(2S)-1-Methyl-2-piperidinyl]ethyl]phenyl]-3-phenyl-2-propenamide (1) (S)-2′[2-1-(methyl-2-piperidyl) ethyl] cinnamanilide...
View ArticleClik here to view.
PDE4 Inhibitor, SB-207499, Cilomilast……….REVISTED
Cilomilast (Ariflo, SB-207,499) cas 153259-65-5 cis-{-4-cyano-4-[3- (trans-3-hydroxycyclopentyloxy)-4-methoxyphenyl]cyclohexane-l -carboxylic acid}...
View ArticleClik here to view.
KAE 609, NITD 609, Cipargamin
Cipargamin, NITD 609 IUPAC Name: (3R,3’S)-5,7′-dichloro-6′-fluoro-3′-methylspiro[1H-indole-3,1′-2,3,4,9-tetrahydropyrido[3,4-b]indole]-2-one | CAS Registry Number: 1193314-23-6 Synonyms: NITD609,...
View ArticleClik here to view.
CMI 977, LDP 977
CMI 977 C16-H19-F-N2-O4 322.3341 Millennium (Originator), Taisho (Licensee) (2S,5S)-1-[4-[5-(4-Fluorophenoxymethyl)tetrahydrofuran-2-yl]-3-butynyl]-1-hydroxyurea 175212-04-1 CMI-977 is a potent...
View ArticleClik here to view.
Ensuring Process Stability with Reactor Temperature Control Systems
Temperature control plays an important role in industrial processes, pilot plants, and chemical and pharmaceutical laboratories. When controlling reactors, both exothermic and endothermic reactions...
View ArticleClik here to view.
Safe Generation and Synthetic Utilization of Hydrazoic Acid in a Continuous...
Safe Generation and Synthetic Utilization of Hydrazoic Acid in a Continuous Flow Reactor. B. Gutmann, J.-P. Roduit, D. Roberge, C. O. Kappe, J. Flow Chem. 2012, 2,8-19....
View ArticleClik here to view.
Arteflene
Arteflene CAS : 123407-36-3 (Z-form) [1S-[1a,4b(Z),5a,8b]]-4-[2-[2,4-Bis(trifluoromethyl)phenyl]ethenyl]-4,8-dimethyl-2,3-dioxabicyclo[3.3.1]nonan-7-one...
View ArticleClik here to view.
Continuous Flow Synthesis of alpha-Halo Ketones: Building Blocks for...
Chiral alpha-halo ketones derived from N-protected amino acids are key building blocks for the synthesis of HIV protease inhibitors such as atazanavir used in HAART combination therapy. Kappe and De...
View ArticleClik here to view.
Meclinertant (SR48692)
2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the...
View ArticleClik here to view.
The application of flow microreactors to the preparation of a family of...
The Application of Flow Microreactors to the Preparation of a Family of Casein Kinase I Inhibitors. Venturoni, F.; Nikbin, N.; Ley S. V.; Baxendale, I. R. Org. Biomol. Chem. 2010, 8, 1798-1806. Link:...
View ArticleClik here to view.
NEW DRUG APPROVALS…….One lakh viewers in USA
Filed under: BLOGS Tagged: Anthony crasto, USA
View ArticleClik here to view.
Fanetizole
Fanetizole Fanetizole shows immunoregulating activity. RN: 79069-95-7 Fanetizole mesylate [USAN] CP-48,810-27 Fanetizole mesylate UNII-D3OG7B0G4M Synthesis Thioureas serve as a convenient starting...
View ArticleClik here to view.
A Method to Identify Best Available Technologies (BAT) for Hydrogenation...
J. Flow Chem. 2012, 2(3), 77–82 http://www.akademiai.com/content/8652651g3378x686/?p=ab7c1bc4cd7740e1855623297649f542&pi=3 http://www.akademiai.com/content/8652651g3378x686/fulltext.pdf Journal of...
View ArticleClik here to view.
Important Industrial Procedures Revisited in Flow: Very Efficient Oxidation...
http://www.akademiai.com/content/u87p126856085276/?p=2f48c96a10a64882aeb5c47c657a10b7&pi=4 Journal Journal of Flow Chemistry Publisher Akadémiai Kiadó ISSN 2062-249X (Print) 2063-0212 (Online)...
View Article