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2014 in review
The WordPress.com stats helper monkeys prepared a 2014 annual report for this blog. Here’s an excerpt: The Louvre Museum has 8.5 million visitors per year. This blog was viewed about 350,000 times in...
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Epelsiban being developed by GlaxoSmithKline for the treatment of premature...
Epelsiban 557296 GSK-557296 GSK-557296-B (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione...
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A PdCl2-Based Hydrogenation Catalyst for Glass Microreactors
A PdCl2-Based Hydrogenation Catalyst for Glass Microreactors Journal Journal of Flow Chemistry Publisher Akadémiai Kiadó ISSN 2062-249X (Print) 2063-0212 (Online) Subject Flow Chemistry Issue Volume...
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The Chemistry of Love
Originally posted on Life is Chemistry: I was sitting in the lobby of my accountant’s office, flipping absentmindedly through a magazine when she walked in. I’ve never had a visceral reaction as when...
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CARIPRAZINE for major depressive disorder
CARIPRAZINE CAS 839712-12-8 (free base) CAS 1083076-69-0…HYDROCLORIDE SALT trans-N-[4-[2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-N’,N’-dimethylurea...
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ICH announces Q&A Document on Q11 Guideline – Main Focus: API Starting Materials
The ICH has recently published a Business Plan and a Concept Paper on the elaboration of a Q&A document on the ICH Q11 Guideline. Read more here....
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Verteporfin
Visudyne, Verteporfin, Verteporfina, Verteporfine, Verteporfinum, Visudine, BPD verteporfin Molecular Formula: C41H42N4O8 Molecular Weight: 718.79418 g/mol 129497-78-5 Benzoporphyrin derivative...
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Entinostat
Entinostat Also known as: ms-275, 209783-80-2, SNDX-275, MS 275, MS-27-275, SNDX 275, NSC-706995 Molecular Formula: C21H20N4O3 Molecular Weight: 376.4085 g/mol pyridin-3-ylmethyl...
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Daiichi Sankyo receives FDA approval for anti-clotting drug Savaysa , EDOXABAN
Edoxaban, DU-176b Daiichi Sankyo receives FDA approval for anti-clotting drug Savaysa Japanese drug-maker Daiichi Sankyo has obtained approval from US Food and Drug Administration (FDA) for its...
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Sandoz’s Zarzio (filgrastim) would be the first ‘biosimilar’ drug available...
A key advisory committee of the US Food and Drug Administration (FDA) has voted in favour of licencing a copycat version of a biological drug. If approved, Sandoz’s Zarxio (filgrastim) would be the...
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Dorzolamide Hydrochloride
Trusopt, 120279-96-1, 1cil, Trusopt (TN), Dorzolamide (DZA), Dorzolamide (INN), MK507 Molecular Formula:C10H16N2O4S3 Molecular Weight:324.44004 g/mol...
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LY-156735 (TIK-301, PD-6735)
N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide 118702-11-7 LY-156735 (TIK-301, PD-6735) is a melatonin MT1 and MT2 agonist which is under development for the treatment of insomnia and...
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N-{2-[7-(Cyclohexylmethyl)-1,6-dihydro-2H-indeno[5,4-b]furan-8-yl]ethyl}aceta...
N-[2-(7-Benzyl-1,6-dihydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acetamide N-{2-[7-(Cyclohexylmethyl)-1,6-dihydro-2H-indeno[5,4-b]furan-8-yl]ethyl}acetamide Acetamide,...
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Rupatadine
Rupatadine CAS 158876-82-5, 8-Chloro-11-(1-((5-methylpyridin-3-yl)methyl)piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine,...
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Novartis obtains European approval for Cosentyx to treat psoriasis
Novartis obtains European approval for Cosentyx to treat psoriasis Swiss drug-maker Novartis has received approval from the European Commission (EC) for its Cosentyx (secukinumab, formerly known as...
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Logistics of process R&D: transforming laboratory methods to manufacturing scale
The manufacture of a | omeprazole (racemic product; top), and esomeprazole (the (S)-enantiomer; bottom), including b | a flow chart of the process for the … Nature Reviews Drug Discovery 2, 654-664...
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Labeling under flow conditions: Understanding added applications
Originally posted on SynthFlow: Stepping outside traditional synthetic labs into specialty applications is not always something we are looking for in the literature, but it is an excellent way to see...
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Ayurveda………..Medicinal Benefits of Liquorice (Mulethi) (मुलेठी, 甘草, شیرین بیان)
Licorice or Mulethi is a medicinal herb which is used in various Ayurvedic medicines. Its underground stems and roots are used for medicinal purpose. It has antioxidant, antimicrobial,...
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AZD 9291 Third-generation, oral, irreversible, selective epidermal growth...
Originally posted on New Drug Approvals: AZD 9291 2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-...
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Zibotentan
186497-07-4, ZD4054, ZD-4054, Zd 4054, ZD4054, Zibotentan Molecular Formula:C19H16N6O4S Molecular Weight:424.43314 g/mol...
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