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Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal...
LY 3000328 Eli Lilly….INNOVATOR (3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl methylcarbamate Specific rotation: [α]D25 = 55.19 (c = 10,DMSO). Cathepsin S (Cat S) plays an important...
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Selective inhibitors of the Janus kinase Jak3—Are they effective?
Selective inhibitors of the Janus kinase Jak3—Are they effective? Bioorganic & Medicinal Chemistry Letters Volume 24, Issue 19, 1 October 2014, Pages 4617–4621 DOI: 10.1016/j.bmcl.2014.08.046...
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Synthesis, biological evaluation and docking analysis of...
COMPD HAS cas no 1616882-93-9 MF……….C18 H11 F3 N2 O2 [1]Benzopyrano[4,3-c]pyrazol-4(1H)-one, 3-methyl-1-[4-(trifluoromethyl)phenyl]-...
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Ibritumomab tiuxetan
Ibritumomab tiuxetan, sold under the trade name Zevalin, is a monoclonal antibody radioimmunotherapy treatment for relapsed or refractory, low grade or transformed B cell non-Hodgkin’s lymphoma, a...
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A CASE OF ICHCHTHYOSIS ; A TYPICAL SKIN DISORDER ; E.T.G AYURVEDASCAN TEST...
Originally posted on आयुर्वेद : आयुष ; ई०टी०जी० आयुर्वेदास्कैन : AYURVEDA : E.T.G. AyurvedaScan ; आयुष आविष्कार ; ई० एच० जी० होम्योपैथीस्कैन : E.H.G. HomoeopathyScan: चर्म रोग ICHCHTHYOSIS या...
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Pharmaceuticals; Make in India
PM, MODI Brand India Pharma aims to make the most of a booming domestic pharma industry India’s pharma exports stood at 90,000 crore rupees ($15 billion) for the year 2013-2014, and are set to cross...
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Amgen files ‘breakthrough’ leukaemia drug Blinatumomab (AMG103) in the US
Blinatumomab Biotechnology giant Amgen has filed its investigational cancer immunotherapy blinatumomab in the US for the treatment of certain forms of acute lymphoblastic leukaemia (ALL)....
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Pirenperone, R 47465
ON THE LEFT OR ABOVE IS 3-(2- {4-[(4-fluorophenyl)carbonyl]piperidin- 1 -yl} ethyl)-2-methyl-4H-pyrido[ 1 ,2- α]pyrimidin-4-one...
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How to identify Out-of-Trend Results in Stability Studies?
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: How to identify Out-of-Trend Results in Stability...
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WHO publishes New Version of the Draft on “Hold-Time” Studies
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: WHO publishes New Version of the Draft on “Hold-Time” Studies...
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FDA Approves Tybost (cobicistat) for use in the treatment of HIV-1 Infection
Cobicistat, GS-9350 1004316-88-4 C 40 H 53 N 7 O 5 S 2 N-[1(R)-Benzyl-4(R)-[2(S)-[3-(2-isopropylthiazol-4-ylmethyl)-3-methyl]ureido]-4-(4-morpholinyl)butyramido]-5-phenylpentyl]carbamic acid...
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FDA Approves Spiriva Respimat (tiotropium) for the Maintenance Treatment of COPD
Ridgefield, Conn., September 25, 2014 – Boehringer Ingelheim Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) approved Spiriva Respimat (tiotropium bromide)...
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FDA Approves Vitekta (elvitegravir) for HIV-1 Infection
FDA Approves Vitekta (elvitegravir) for HIV-1 Infection September 24, 2014 — The U.S. Food and Drug Administration (FDA) has approved Vitekta (elvitegravir), an integrase strand transfer inhibitor...
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QP Declaration: EMA publishes Comments
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: QP Declaration: EMA publishes Comments...
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LEXANOPADOL, For Treatment of acute and chronic pain requiring opioid analgesia
LEXANOPADOL trans-6′-Fluoro-N-methyl-4-phenyl-4′,9′-dihydro-3’H-spiro(cyclohexane-1,1′-pyrano(3,4-b)indol)-4-amine Spiro(cyclohexane-1,1′(3’H)-pyrano(3,4-b)indol)-4-amine,...
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Nicox stock leaps on positive Ph III glaucoma drug data , 英文名称
latanoprostene bunod, 英文名称 4- (nitrooxy) butyl (5Z) -7 – {(1R, 2R, 3R, 5S) -3,5-dihydroxy-2 – [(3R) -3-hydroxy-5-phenylpentyl] cyclopentyl} hept-5- enoate CAS No.860005-21-6 Formula C 27 H 41 NO 8...
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6 Tastes to Stop Food Cravings!
Originally posted on Veda Health: GOT FOOD CRAVINGS? CHECK OUT MY ARTICLE ON THE 6 TASTES THAT SHOULD BE IN EVERY MEAL TO CUT OUT PESKY FOOD CRAVINGS View originalFiled under: Uncategorized
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(S)-Atenolol
(S)-atenolol Description Selective β1 adrenoceptor antagonist Biological descriptionSelective β1 adrenoceptor antagonist. Orally active. Limited ability to cross the blood-brain barrier....
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Organic Process Research and Development – India, The 32nd International...
WEBSITE http://www.scientificupdate.co.uk/ SCIENTIFIC UPDATE HAS A REPUTATION FOR ITS HIGH QUALITY EVENTS, BOTH FOR THE SCIENTIFIC CONTENT AND ALSO FOR THE EFFICIENCY OF ITS ORGANISATION. KEEP YOUR...
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Welcome Scientific update to Pune, India 2-3 and 4-5 Dec 2014 for celebrating...
WEBSITE http://www.scientificupdate.co.uk/ SCIENTIFIC UPDATE HAS A REPUTATION FOR ITS HIGH QUALITY EVENTS, BOTH FOR THE SCIENTIFIC CONTENT AND ALSO FOR THE EFFICIENCY OF ITS ORGANISATION. KEEP YOUR...
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