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Quarfloxin, Itarnafloxin , CX-3543….Inhibits rRNA biogenesis.
Quarfloxin, Itarnafloxin CAS: 865311-47-3. Chemical Formula: C35H33FN6O3 Exact Mass: 604.25982 Molecular Weight: 604.67 Elemental Analysis: C, 69.52; H, 5.50; F, 3.14; N, 13.90; O, 7.94 Synonym:...
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Mitsubishi Tanabe And EnVivo in Phase III Trial Of Alzheimer’s Disease...
OR Encenicline (EVP-6124, MT-4666) EVP-6124 , MT-4666, α7-nAChR agonist, UNII-5FI5376A0X Chemical Name: (R)-7-chloro-N-quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide Therapy Type: Small Molecule...
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AMIODARONE
Amiodarone CAS : 1951-25-3 (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone 2-butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone;...
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Acai counteracts oxidative stress, lengthens lifespan in fruit flies
Originally posted on Clinicalnews.org: 24 AUG 2012 Bewildered by the array of antioxidant fruit juices on display in the supermarket and the promises they make? To sort out the antioxidant properties...
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FDA approves AstraZeneca’s constipation drug Movantik
September 16, 2014 Kevin Grogan The US Food and Drug Administration has approved AstraZeneca’s Movantik for opioid-induced constipation in adults with chronic non-cancer pain. Movantik (naloxegol), an...
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CARMEGLIPTIN………….a DPP-4 inhibitor
(2S,3S,11βS)-1-(2-Amino-9,10-dimethoxy-1,3,4,6,7,11β-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-(4S)-fluoromethyl-pyrrolidin-2-one Dihydrochloride...
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Glenmark’s TRPA1 antagonist ‘GRC 17536’ shows positive data in a proof of...
MUMBAI, India, Sep 17, 2014 - Glenmark's first in class TRPA1 antagonist, GRC 17536, has shown positive data in a Phase 2a proof of concept study in patients with painful diabetic neuropathy...
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FDA publishes ICH Q4B – Annex 6 on Uniformity of Dosage Units
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: GMP News: FDA publishes ICH Q4B – Annex 6 on Uniformity of Dosage Units...
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If a Facility stores Medicinal Products for more than 36 Hours GDP will apply
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: GMP News: If a Facility stores Medicinal Products for more than 36 Hours GDP will apply...
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Complaints and Recalls: new EU-GMP Chapter 8 published
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: GMP News: Complaints and Recalls: new EU-GMP Chapter 8 published...
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Talaglumetad hydrochloride
Talaglumetad hydrochloride Formula C11H16N2O5. HCl Exact mass 292.0826 Mol weight 292.7161 CAS: 441765-97-5 441765-98-6 (free base) IUPAC Name:...
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Sun Pharma, Merck & Co Inc ink pact for Tildrakizumab
Sep 17, 2014, Under terms of the agreement, Sun Pharma will acquire worldwide rights to tildrakizumab for use in all human indications from Merck in exchange for an upfront payment of USD 80...
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Coconut water is an excellent sports drink — for light exercise
Originally posted on Clinicalnews.org: PHILADELPHIA, Aug. 20, 2012 — Coconut water really does deserve its popular reputation as Mother Nature’s own sports drink, a new scientific analysis of the...
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FDA Approves Trulicity (dulaglutide) for Type 2 Diabetes
FDA Approves Trulicity (dulaglutide) for Type 2 Diabetes DULAGLUTIDE PRONUNCIATION doo” la gloo’ tide THERAPEUTIC CLAIM Treatment of type II diabetes CHEMICAL NAMES 1. 7-37-Glucagon-like peptide I...
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Wild berry extract may strengthen effectiveness of pancreatic cancer drug
Originally posted on Clinicalnews.org: Public Release: 17-Sep-2014 The findings prompt the researchers to suggest that adding ‘nutraceuticals’ to chemotherapy cycles may improve the effectiveness of...
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Dasotraline, 1R,4S Transnorsertraline, SEP-225289………For treatment of...
Dasotraline, SEP-225289, DSP-225289 1R,4S Transnorsertraline Generic Name:Dasotraline Synonym: SEP-225289 Chemical Name:(1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine...
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Leflunomide
Leflunomide RS-34821, SU-101, HWA-486, Arava,75706-12-6, C12-H9-F3-N2-O2 270.2091 Aventis Pharma (Originator), Lepetit , Kyorin (Licensee), Sugen (Licensee) Antiarthritic Drugs, Brain Cancer Therapy,...
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INCB-039110, Janus kinase-1 (JAK-1) inhibitor……..for the treatment of...
INCB-39110, CAS 1334298-90-6 INCB-039110, Jak1 tyrosine kinase inhibitor 3-Azetidineacetonitrile,...
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EU OK’s Gilead’s rare blood cancers drug
SEPT 21 , 2014 Patients with the incurable blood cancers chronic lymphocytic leukaemia (CLL) and follicular lymphoma (FL) have gained access to a new treatment option in Europe with the approval of...
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