Clik here to view.
21′α-Cyanoanhydrovinblastine
Some derivatives ) are known as being intermediates in the preparation of anti-tumor medicaments such as vinblastine, vincristine and vinorelbine. R=CH3, vinblastine R=CHO, vincristine n=2,...
View ArticleClik here to view.
AMRI Introduces Protein Expression & Purification Solutions
A MESSAGE FROM MICHAEL A. LUTHER, SENIOR VICE PRESIDENT DISCOVERY AND DEVELOPMENT Dear Anthony,As a company with a deep history of discovery innovation, Albany...
View ArticleClik here to view.
EU Commission publishes long-awaited EU GMP Guide Chapters 3 and 5
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: The EU Commission has published the long-awaited, revised chapters 3 and 5 of the EU GMP Guide. The change focuses on the prevention of...
View ArticleClik here to view.
Questions and Answers on the Topic “Pharmaceutical Water”
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: In the following News, you will find questions on pharmaceutical water preparation and distribution frequently asked during our courses,...
View ArticleClik here to view.
MHRA’s Guidance for Software as a Medical Device (including Apps)
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: The British MHRA (Medicines and Healthcare Products Regulatory Agency) has published a guidance for developers of “software as a medical...
View ArticleClik here to view.
RAVUCONAZOLE
Ravuconazole BMS-207147, ER-30346 BMS 207147 ER 30346 Ravuconazole UNII-95YH599JWV CAS Registry Number: 182760-06-1 CAS Name:...
View ArticleClik here to view.
Fosravuconazole in phase 1 for the treatment of fungal infections.
Fosravuconazole Phosphoric acid 2(R)-[4-(4-cyanophenyl)thiazol-2-yl]-1(R)-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-ylmethyl)propyoxymethyl monoester...
View ArticleClik here to view.
Tioconazole UK-20349 an antifungal agent
Tioconazole;UK-20349;Trosyd;Trosyl;Vagistat-1 l-[2-(2-chloro-3-thienyl)methoxy]-2-(2,4- dichlorophenyl)ethyl]-lH-imidazole,...
View ArticleClik here to view.
Tecadenoson…………Atrial Fibrillation
Tecadenoson CAS : 204512-90-3 N-[(3R)-Tetrahydro-3-furanyl]adenosine (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol N-(3-Tetrahydrofuranyl)-6-aminopurine...
View ArticleClik here to view.
Infinity and AbbVie partner to develop and commercialise Duvelisib for...
Duvelisib Infinity and AbbVie partner to develop and commercialise duvelisib for cancer INK 1197; IPI 145; 8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone...
View ArticleClik here to view.
Albaconazole
Albaconazole Also known as: UNII-YDW24Y8IAB; UR-9825; 187949-02-6; UR 9825, W-0027 Molecular Formula: C20H16ClF2N5O2 Molecular Weight: 431.823146...
View ArticleClik here to view.
Teva’s Asthma Drug ‘Significantly’ Improves Lung Function In Phase 3 Trials
// Reslizumab CAS 241473-69-8 PETAH TIKVA (dpa-AFX) – Teva Pharmaceutical Industries Ltd. (TEVA) Monday said asthma patients with elevated eosinophils showed significant improvement in lung function...
View ArticleClik here to view.
New Route to Paricalcitol
Synthesis offers potential routes to analogues of vitamin-D-based drug Paricalcitol, an A-ring-modified 19-nor analogue of 1α,25-dihydroxyvitamin D2, is currently used for the treatment and prevention...
View ArticleClik here to view.
IMATINIB
Imatinib CAS No:- [152459-95-5] IUPAC Name:- 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide M. P.:- 211-213 °C MW: 493.604...
View ArticleClik here to view.
Commentary Regarding new USP Chapters and for Particulate Matter Guidance
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Commentary Regarding new USP Chapters and for Particulate Matter Guidance There are new chapters in the USP regarding testing of...
View ArticleClik here to view.
Still a GMP problem? Or already a criminal act? Do we need more stringent...
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Still a GMP problem? Or already a criminal act? Do we need more stringent measures and enforcement in certain situations? Sometimes EU and...
View ArticleClik here to view.
GMP Question & Answer Guide
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: GMP Question & Answer Guide The requirements defined in the GMP Guidelines often leave room for interpretation. However, regulators...
View ArticleClik here to view.
Hydrogenation in flow: homogenous and heterogeneous catalysts using Teflon...
Hydrogenation in flow: homogenous and heterogeneous catalysts using Teflon AF-2400 to effect gas-liquid contact at elevated pressure...
View ArticleClik here to view.
LAPATINIB, GW572016, An EGFR-ErbB-2 inhibitor.
LAPATINIB Title: Lapatinib CAS Registry Number: 231277-92-2 CAS Name: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine...
View ArticleClik here to view.
Piramal Drops Drug Discovery,…………. Pharmaceuticals: Risks and regulations...
A Piramal scientist at work in Mumbai last month. Credit: Danish Siddiqui/Reuters/Newscom In a move that raises questions about the future of drug research in India, Piramal Enterprises will end its...
View Article