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Regeneron and Sanofi’s dupilumab gets FDA breakthrough therapy status for...
// // // Regeneron Pharmaceuticals and Sanofi’s dupilumab has received breakthrough therapy designation from US Food and Drug Administration (FDA) to treat adults with moderate-to-severe atopic...
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DUTOGLIPTIN
Dutogliptin tartrate Syn name: 1-[N-[3(R)-Pyrrolidinyl]glycyl]pyrrolidin-2(R)-ylboronic acid L-tartrate Cas number: 890402-81-0 Molecular Formula: C14H26BN3O9 Molecular Weight: 391.18 DUTOGLIPTIN...
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DENAGLIPTIN
DENAGLIPTIN (2S,4S)-1-[(2S)-2- amino-3,3-bis(4-fluorophenyl)propionyl]-4-fluoropyrrolidine-2-carbonitrile, (2S,4S)-4-fluoro-1-[4-fluoro-beta-(4-fluorophenyl)-L-phenylalanyl]-2-pyrrolidinecarbonitrile...
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NAVEGLITAZAR (LY519818)
NAVEGLITAZAR 2(S)-Methoxy-3-[4-[3-(4-phenoxyphenoxy)propoxy]phenyl]propionic acid 476436-68-7 C25 H26 O6, 422.4703 CCRIS 9448 LY 519818 LY 9818 LY519818 LY9818 Naveglitazar UNII-Y995M7GM0G...
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NETOGLITAZONE
NETOGLITAZONE, isaglitazone 161600-01-7 5-((6-((2-fluorophenyl)methoxy)-2-naphthalenyl)methyl)-2,4-thiazolidinedione MCC 555 MCC-555 netoglitazone RWJ-241947 Netoglitazone (MCC-555) is a...
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EU approves Lilly diabetes drug Trulicity, dulaglutide
Regulators in Europe have given the green light to Eli Lilly’s Trulicity, its once-weekly glucagon-like peptide-1 receptor agonist for type 2 diabetes. Read more at:...
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KEBUZONE…….An antirheumatic agent.
Kebuzone (or ketophenylbutazone) is a non-steroidal anti-inflammatory drug. Structural formula 4-(3-oxobutyl)-1,2-diphenylpyrazolidine-3,5-dione UNII-4VD83UL6Y6 853-34-9...
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Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles as an...
Scheme 1: Synthesis of ibuprofen using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs) using ethanol and pyridine in their reactions. Synthesis of Ibuprofen Using...
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Janssen seeks FDA approval for Yondelis (Trabectedin) drug to treat advanced STS
ET-743, Yondelis (trabectedin) Trabectedin, Ecteinascidin 743, NSC-684766, ET-743, Yondelis, ID0YZQ2TCP cas 114899-77-3...
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I did not run away from a NaCN Exotherm
DELTAMETHRIN DID NOT RUN AWAY FROM NACN ie sodium cyanide EXOTHERM ALMOST VIRTUAL ACCIDENT AT RPG LIFESCIENCES (SEARLE) PANOLI GUJARAT INDIA 1999-2000 DELTAMETHRIN PROJECT, 1999-2000 Panoli Gujarat...
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Cefditoren pivoxil
Cefditoren pivoxil ME-1207, Spectracef, Meiact 117467-28-4 (-)-(6R,7R)-2,2-dimethylpropionyloxymethyl...
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YM758 Monophosphate, A Novel If Channel Inhibitor
(−)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide monophosphate (YM758 monophosphate,...
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2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists
((2R,3aR,6aR)-2-((3R,4R)-3-Methoxytetrahydro-2H-pyran-4-ylamino)octahydropentalen-3a-yl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone...
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A Flow Reactor with Inline Analytics: Design and Implementation
A Flow Reactor with Inline Analytics: Design and Implementation Org. Process Res. Dev., 2014, 18 (11), pp 1315–1320 DOI: 10.1021/op5002512 Kristina Somerville, Michael Tilley, Guanlong Li, Debasis...
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Ramatroban
Ramatroban CAS 116649-85-5 (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid (+)-(3R)-3-(p-fluorobenzenesulfonamido)-1,2,3,4-tetrahydrocarbazole-9-propionic...
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BENDAMUSTINE
Bendamustine CAS : 16506-27-7 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid g-[1-methyl-5-[bis(b-chloroethyl)amino]-2-benzimidazolyl]butyric acid MF C16H21Cl2N3O2 MW 358.26...
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IMPROVED CONTINUOUS FLOW PROCESSING: BENZIMIDAZOLE RING FORMATION VIA...
Originally posted on ORGANIC CHEMISTRY SELECT: Improved Continuous Flow Processing: Benzimidazole Ring Formation via Catalytic Hydrogenation of an Aromatic Nitro Compound...
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Sanofi Gets US FDA Approval For Priftin, Rifapentine 利福喷汀 Tablets To Treat...
French drug maker Sanofi Tuesday said it has received approval from the U.S. Food and Drug Administration for its Priftin (rifapentine) tablets to treat latent tuberculosis infection, or LTBI....
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Pi-Process Intensification Experts LLP at CPhI Mumbai India 3rd Dec 2014…My...
I (Dr Anthony) seated with Dr Vijay Kirpalani CEO of Pi-Process Intensification Experts LLP at CPhI Mumbai India 3rd Dec 2014 Pi-Process Intensification Experts LLP provide Process Intensification...
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US FDA issued a Warning Letter to the company Hikma Pharmaceuticals
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Warning Letter: Deficiencies in Visual Inspection In October 2014, the US FDA issued a Warning Letter to the company Hikma Pharmaceuticals...
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